Pharmaceutical composition of (r)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxy propyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration therof

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

ALARGOVA ROSSITZA GUEORGUIEVA,DUNBAR CRAIG ANTONY,KADIYALA IRINA NIKOLAEVNA

申请号：

NZ60680511

公开号：

NZ606805A

申请日:

2011.08.22

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Provided is a pharmaceutical composition comprising (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide (formula 1), a filler, a diluent, a disintegrant, and a glidant in the form of a tablet. The pharmaceutical composition may be used in the treatment of cystic fibrosis.

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