A device for drawing tissues together and creating an anastomosis comprises a main guide wire (66,86) suitable to receive and draw together portions (AB) of tissues to be joined by means of anastomosis. The main guide wire (66, 86) is suitable to be shaped like an open ring crossing the portions (A, A" B, B") of tissues to be joined by means of anastomosis (66,86), wherein the ends of the main guide wire (66,86) are different and distinguishable from each other. The main guide wire (66, 86) has a tubular or hollow structure suitable to house at least one needle for a push or radiofrequency perforation of the tissue.