Jingsong Chen;Gregory H. Altman;Rebecca Horan;David J. Horan
发明人:
Gregory H. Altman,Jingsong Chen,Rebecca Horan,David J. Horan
申请号：
US13561949
公开号：
US20120296443A1
申请日:
2012.07.30
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Silk is purified to eliminate immunogenic components (particularly sericin) and is used to form fabric that is used to form tissue-supporting prosthetic devices for implantation. The fabrics can carry functional groups, drugs, and other biological reagents. Applications include hernia repair, tissue wall reconstruction, and organ support, such as bladder slings. The silk fibers are arranged in parallel and, optionally, intertwined (e.g., twisted) to form a construct； sericin may be extracted at any point during the formation of the fabric, leaving a construct of silk fibroin fibers having excellent tensile strength and other mechanical properties.
