Steven Elmore,Andrew Souers,Lichun Wang,Tariq Ghayur,Stuart J. Perper
申请号:
US15838605
公开号:
US20180369250A1
申请日:
2017.12.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This invention pertains to methods of treating systemic lupus erythematosus and Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-XL.