Yung-Hsiang KAO,Michael W. LAIRD,Melody Trexler SCHMIDT,Rita L. WONG,Daniel P. HEWITT
申请号：
US16847309
公开号：
US20200317801A1
申请日:
2020.04.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.
