Combination therapies for treatment of cancers associated with mutations in the KRAS gene are provided. Compositions comprising therapeutic agents for treatment of cancers associated with mutations in the KRAS gene are also provided本發明提供用於治療與KRAS基因突變相關之癌症的組合療法。亦提供包含用於治療與KRAS基因突變相關之癌症之治療劑的組合物。