A normal light CCD 11 is driven via a normal light CCD control section 25 by a timing signal from a timing circuit section 29 of a video processor 20. At the same time, a fluorescence CCD 12 is driven via a fluorescence CCD control section 26. Then, an image pickup signal according to an RGB frame sequential method from the normal light CCD 11 is processed by a normal light image video circuit section 27 and a normal color image is created while an image pickup signal from the fluorescence CCD 12 is processed by a fluorescence image video circuit section 28, and an image pickup signal of a subject excited by blue illumination light and transmitted through a fluorescence transmitting filter 13 is extracted to create a fluorescence image of the subject. The normal color image and the fluorescence image of the subject are synthesized by an image synthesizing circuit section 30 and outputted to a monitor 2, whereby the normal light image and the fluorescence image is displayed side by side or on top of each other.
