Jae Kwan Song,Eun Ju Chang,Mi Jeong Kim,Bongkun Choi,Sahmin Lee
申请号：
US14473618
公开号：
US09416196B2
申请日:
2014.08.29
申请国别(地区):
US
年份:
2016
代理人:
摘要：
There is provided a composition for prophylaxis or treatment of vascular or valvular calcification including a dipeptidylpeptidase-4 (DPP-4) inhibitor. The DPP-4 according to one exemplary embodiment of the present disclosure is expressed at an increased level when blood vessels and valves are calcified, and the calcification decreases remarkably upon administration of the DPP-4 inhibitor. Therefore, the DPP-4 inhibitor can be useful in treatment or prophylaxis of blood vessels or valves.
