ANTI PDGFR-ALPHA ANTIBODY, NUCLEIC ACID ENCODING THE SAME, VECTOR COMPRISING SAID NUCLEIC ACID, HOST CELL COMPRISING SAID VECTOR, CONJUGATE OF SAID ANTIBODY AND USE OF THE SAID ANTIBODY IN THE PREPARATION OF MEDICAMENTS
ASTRAZENECA AB;DAVID CHARLES BLAKEY;GADI GAZIT-BORNSTEIN;XIADONG YANG;SUSAN ANN CARTLIDGE;NAOMI LAING;JASPAL SINGH KANG;IAN FOLTZ;LAURA TAYLOR
发明人:
DAVID CHARLES BLAKEY,GADI GAZIT-BORNSTEIN,XIADONG YANG,SUSAN ANN CARTLIDGE,NAOMI LAING,JASPAL SINGH KANG,IAN FOLTZ,LAURA TAYLOR
申请号:
IL19620908
公开号:
IL196209A
申请日:
2008.12.25
申请国别(地区):
IL
年份:
2013
代理人:
摘要:
Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.