KALDOR, Stephen W.,VEAL, James Marvin,CHEN, Young K.,KANOUNI, Toufike,STAFFORD, Jefrey Alan
申请号：
CL2016002736
公开号：
CL2016002736A1
申请日:
2016.10.27
申请国别(地区):
CL
年份:
2017
代理人:
摘要：
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer.COMPUESTOS CON ACTIVIDAD INHIBIDORA DE LISINA (LSD-1)； COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE； ÚTILES EN EL TRATAMIENTO DEL CÁNCER, TAL COMO LEUCEMIA MIELOIDE AGUDA (AML), NEUROBLASTOMA, TUMORES DE CÉLULAS AZULES REDONDAS PEQUEÑAS, GLIOBLASTOMA, CÁNCER DE PRÓSTATA, CÁNCER DE MAMA, CÁNCER DE VEJIGA, ENTRE OTROS.
