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COMPOSITION DE LIPOSOMES LIPIDIQUES
专利权人:
TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE; LTD.;JCR PHARMACEUTICALS CO., LTD.;JCR PHARMACEUTICALS CO.
发明人:
SAKURABA, HITOSHI,TAJIMA, YOUICHI,KAWASHIMA, IKUO,ITO, MAI,TAKEOKA, SHINJI,OHTA, KATSUJI,ITO, MANABU,MIZUNO, ATSUSHI
申请号:
EP06746576
公开号:
EP1889628A4
申请日:
2006.05.11
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can be used effectively in enzyme replacement therapy or the like. This problem is solved by a lipid vesicle composition wherein vesicles composed of a lipid bilayer membrane are encapsulating an enzyme, the composition being capable of retaining stably the activity of the enzyme even outside the stable pH range of the enzyme.
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中国工程科技知识中心
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