Hongyong Zhang;Kit S. Lam;Olulanu H. Aina;Chong-xian Pan
发明人:
Chong-xian Pan,Hongyong Zhang,Kit S. Lam,Olulanu H. Aina
申请号:
US13497041
公开号:
US20120230994A1
申请日:
2010.09.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO:1), and methods of their use, e.g., for imaging detection for diagnosis of bladder, tumor localization to guide transurethral resection of bladder cancer, imaging detection of bladder cancer for follow-up after the initial treatment that can replace or complement costly cystoscopy, imaging detection of metastatic bladder cancer, and targeted therapy for superficial and metastatic bladder cancer.