TSAI; RAY JUI-FANG;TSAI, RAY JUI-FANG;TSENG, SCHEFFER C. G.
发明人:
TSAI, RAY JUI-FANG,TSENG, SCHEFFER C. G.
申请号:
CA2406282
公开号:
CA2406282C
申请日:
2001.04.25
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Transplantation of epithelial stem cells, cultured ex vivo on specificallytreated amniotic membrane, yields, with that amniotic membrane, a surgicalgraft having expanded epithelial stem cells. The method of creating this graftand the graft itself provide simple and effective means to reconstruct damagedtissue, a preferred example being corneal tissue. The source of the epithelialstem cells can be a very small explant from healthy autologous and allogeneictissue biopsy. The amniotic membrane is treated such that its extracellularmatrix is maintained, but its cells are killed.