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תכשיר רוקחות או תוסף תזונה עמיד בקיבה עם עמידות בפני השפעה של אתנול
专利权人:
EVONIK ROHM GMBH
发明人:
申请号:
IL22839613
公开号:
IL228396D0
申请日:
2013.09.12
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
The invention discloses a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the gastric resistant coating layer comprises at least 30% by weight of a (meth)acrylate copolymer comprising polymerized units of 10 to 40% by weight of acrylic or methacrylic acid, 10 to 80% by weight of a C4- to C18-alkyl ester of acrylic or methacrylic acid and optionally 0 to 60% by weight of another vinylic monomer, whereby the release of the pharmaceutical or nutraceutical active ingredient is not more than 10% under in-vitro conditions at pH 1.2 after 2 hours in medium according to USP with and without the addition of 20% (v/v) ethanol.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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