A system for a pneumatically-powered vitrectomy machine includes an output port, a venting valve, a venting manifold, a pressure transducer, and a controller. The output port provides pressurized gas to a vitrectomy probe. The venting valve is located close to the output port. The venting manifold fluidly connects the venting valve to a venting port. The venting port vents pressurized gas from the venting manifold. The pressure transducer is located near the output port. The pressure transducer is configured to read a pressure of a gas near the output port. The controller is adapted to receive information about the pressure and activate the venting valve. When the information received from the pressure transducer indicates a fault condition, the controller directs the venting valve to open.