The present invention relates to a synergistic herbicidal composition comprising; (A) mesotrione, and: (B) a second herbicide selected form; (B1) triazines (B2) triazolinones (B3) triazinones (B4) imidazolinones (B5) dicamba (B6) flumetsulam (B7) trifloxysulfuron (B8) tritosulfuron (B9) triasulfuron (B10) pyriftalid (B11) prosulfocarb (B12) pretilachlor (B13) cinosulfuron, or their herbicidally effective salts. A method of controlling th growth of undesirable vegetation, particularly in crops, using this synergistic composition is also disclosed.