Conor L. Evans,Gabriela Apiou,Alexander J. Nichols,Emmanouil Rousakis,Zongxi Li
申请号：
US14903710
公开号：
US09789206B2
申请日:
2014.06.13
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compounds, systems, and methods are provided for a non-invasive, analyte sensing dressing. The dressing includes a sensor and a matrix. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions. The device emits a detectable signal when the sensor is excited in the presence of the analyte. The sensor may include a meso-unsubstituted metallated porphyrin that is sensitive towards oxygen. The porphyrin can be excited when illuminated at a first wavelength, followed by emission of phosphorescence at a second wavelength whose intensity is an indicator for oxygen concentration. An example metallated porphyrin has the Formula(I):wherein M is a metal, each R is independently an atom or a group of atoms, and at least one R is —OR1, wherein R1 is an atom or a group of atoms.
