Brian P. Pollack,Richard W. Compans,Joanna A. Pulit-Penaloza,Ioanna Skountzou
申请号:
US15024102
公开号:
US20160228533A1
申请日:
2014.09.23
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This disclosure relates to using EGFR pathway inhibitors in combination with compositions comprising an antigen to increase, elicit, or improve an antigen or vaccine-induced immune response. In certain embodiments, the EGFR pathway inhibitor is administered under conditions such that memory cells to the antigen are formed in a subject. In certain embodiments, the composition is a vaccine. In certain embodiments, the EGFR pathway inhibitor and vaccine are administered to the skin epidermis or dermis.