Topical or ocular composition comprises a double stranded RNA oligonucleotide, where the oligonucleotide is associated with a cationic particle (having size of =1 mu m and a zeta potential of 10-80 mV) of surface active micelles, polymer block micelles, non ionic or cationic surface active liposomes, niosomes, oleosomes, nanoemulsions, nanocapsules, organic or inorganic particles. An independent claim is included for a process of cosmetic treatment comprising applying the composition topically or ocularly. ACTIVITY : None given. MECHANISM OF ACTION : None given.
