METHODS AND ANTIBODIES FOR MODULATION OF IMMUNORESPONSE

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专利权人:

Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital

发明人:

Yen-Ta LU,Chia-Ming CHANG,Tsai-Yin WEI,I-Fang TSAI,Ling-Chiao WU

申请号：

US15735912

公开号：

US20180362651A1

申请日:

2016.06.12

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A method fits reversing immune suppression or immune exhaustion or for treating a disease associated with immune suppression includes: administering a co position to a subject in need of such treatments wherein the composition contains a CD11b modulator that binds specifically to CD11b on a cell to inhibit PD-L1 expression. The CD11b modulator is an antibody or an antigen-binding portion thereof, or a compound as described.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/