The United States of America; as represented by the Secretary; Department of Health and Human Servic
发明人:
Marjan Huizing,May C. Malicdan,Nuria Carrillo
申请号：
US16655004
公开号：
US20200046747A1
申请日:
2019.10.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Methods are disclosed for treating a subject with a vascular or cardiac disorder associated with oxidative stress. Methods are disclosed for treating a subject with GNE myopathy that has impaired cardiac function. These methods include administering to the subject a therapeutically effective amount of a sialic acid precursor, sialic acid, or one or more sialylated compounds, mannosamine, N-acetyl mannosamine or a derivative thereof. In other embodiments, methods are disclosed for detecting a disorder associated with oxidative stress.
