Systems and methods which utilize stress first and then rest imaging techniques to provide for improved medical imaging results are provided herein. One embodiment may administer a stress regime, such as exercise stress, and administer a tracer to a patient and retrieve a stress image. Then a second tracer is administered to a patient and a resting image is retrieved. Embodiments may implement this method with PET/CT scanning techniques. Additionally, embodiments may utilize a single CT scan when obtaining both the stress and rest images.
