The present invention relates to pharmaceutical compositions containing at least one protein active ingredient protected from digestive enzymes. Said pharmaceutical compositions contain said at least one protein active ingredient, in free form, as well as, for liquids, a system capable of buffering them to a pH greater than 4 and less than or equal to 8 or, for solids, a system that exerts, when they are placed in a liquid medium, a buffer effect between a pH greater than 4 and a pH less than or equal to 8.本發明係關於一種包含至少一種經保護而免受消化酶影響之蛋白質活性成份之醫藥組合物。該醫藥組合物包含游離型之該至少一種蛋白質活性成份，及用於液體時之一種能在大於4且小於或等於8的pH下進行緩衝之系統，用於固體之一種當其置於液體介質中時，能在大於4的pH與小於或等於8的pH之間發揮緩衝效應之系統。
