Genetically modified photoautotrophic ethanol producing host cells, method for producing the host cells, constructs for the transformation of the host cells, method for testing a photoautotrophic strain for a desired growth property and method of produci

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专利权人:

Algenol Biofuels Inc.

发明人:

Oesterhelt, Christine,Kramer, Dan,Woods, Paul,Enke, Heike,Lockau, Wolfgang,Smith, Craig R.,Grundel, Marianne,Coleman, John Robert,Ziegler, Karl,Duhring, Ulf,Baier, Kerstin

申请号：

AU2014253543

公开号：

AU2014253543A1

申请日:

2014.10.24

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

#$%^&*AU2014253543A120141113.pdf#####GENETICALLY MODIFIED PHOTOAUTOTROPHIC ETHANOL PRODUCING HOST CELLS, METHOD FOR PRODUCING THE HOST CELLS, CONSTRUCTS FOR THE TRANSFORMATION OF THE HOST CELLS, METHOD FOR TESTING A PHOTOAUTOTROPHIC STRAIN FOR A DESIRED GROWTH PROPERTY AND METHOD OF PRODUCING ETHANOL USING THE HOST CELLS Abstract In one embodiment the invention provides a genetically modified photoautotrophic, ethanol producing host cell comprising: - at least one first genetic modification changing the enzymatic activity or affinity of an endogenous host cell enzyme, - the first genetic modification resulting in an enhanced level of biosynthesis of acetaldehyde, pyruvate, acetyl - CoA or precursors thereof compared to the respective wild type host cell, - at least one second genetic modification different from the first genetic modification comprising an overexpressed enzyme for the formation of ethanol. (42l1'；R211-AMC；H

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