Taek-Chin Cheong;Jun Hua Wu;Young-Keun Kim;Ji Hyun Min;Seung-Yong Seong;Nam-Hyuk Cho
发明人:
Nam-Hyuk Cho,Taek-Chin Cheong,Seung-Yong Seong,Ji Hyun Min,Jun Hua Wu,Young-Keun Kim
申请号：
US13505705
公开号：
US09718860B2
申请日:
2010.11.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to a complex of a protein comprising zinc oxide-binding peptides and zinc oxide nanoparticles, to the use thereof as a drug delivery carrier for manufacturing medicines, and to a vaccine composition and a contrast agent comprising the composite. The protein comprising zinc oxide-binding peptides significantly improves the in vivo availability of zinc oxide-binding peptides, and therefore the complex of the present invention can be used not only as a drug delivery carrier for in vivo drug delivery or intracellular drug delivery, but also for in vivo imaging or cell imaging. The complex can be used for producing separating agents for effectively separating biological materials, therapeutic agents for hyperthermia, etc., contrast agents for MRI, and beads applicable to biosensors.
