CALVANI, FEDERICO,CATRAMBONE, FERNANDO,FELICETTI, PATRIZIA,FINCHAM, CHRISTOPHER INGO,GIOLITTI, ALESSANDRO,MAGGI, CARLO ALBERTO,QUARTARA, LAURA,ROSSI, CRISTINA,TERRACCIANO, ROSA
申请号:
CA2488565
公开号:
CA2488565C
申请日:
2003.06.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Non-peptide compounds of formula (I) having activity as specific antagonistsof bradykinin (BK) B2 receptor. The compounds are chemically characterized bythe presence of an alpha, alpha-disubstituted amino acid at least one aminogroup, free or salified, or the corresponding ammonium quaternary salt. TheseBK receptor antagonists are a novel class of medicaments which can be used inall the disorders in which said receptors are involved.