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COMPOSÉS DE 2-AMINOOXAZOLINE COMME LIGANDS DU TAAR1 POUR DES TROUBLES DU SNC
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
申请号:
EP08701646.5
公开号:
EP2114906B1
申请日:
2008.01.23
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The invention relates to compounds of formula I wherein X, Y, R<;SUP>;1<;/SUP>;, R<;SUP>;2<;/SUP>;, and n are as defined herein or to a pharmaceutically suitable acid addition salt thereof. The invention also relates to pharmaceutical compositions containing such compounds and methods for the treatment of diseases related to the biological function of the trace amine associated receptors, which diseases include depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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