BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;PEREGRINE PHARMACEUTICALS, INC.
发明人:
THORPE, PHILIP E.,LUSTER, TROY A.,KING, STEVEN W.
申请号：
CA2591914
公开号：
CA2591914C
申请日:
2006.01.24
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Disclosed are new phosphatidylserine binding constructs with surprisingcombinations of properties, and a range of diagnostic and therapeuticconjugates thereof. The new constructs effectively bind phosphatidylserinetargets in disease and enhance their destruction, and can also specificallydeliver attached imaging or therapeutic agents to the disease site. Alsodisclosed are methods of using the new construct compositions, therapeuticconjugates and combinations thereof in tumor vasculature targeting, cancerdiagnosis and treatment, and for treating viral infections and other diseases.
