CONJUGUES HELICAR-ANTICORPS ANTI-HELICAR LIES DE FACON COVALENTE ET UTILISATIONS ASSOCIEES

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

BRINKMANN, ULRICH,GEORGES, GUY,HOFFMANN, EIKE,TIEFENTHALER, GEORG,MOESSNER, EKKEHARD,DENGL, STEFAN,GAERTNER, ACHIM

申请号：

CA2930154

公开号：

CA2930154A1

申请日:

2014.12.29

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Herein is reported a conjugate comprising a helicar motif amino acid sequence containing compound and an antibody that specifically binds to the helicar motif amino acid sequence characterized by a covalent bond between the helicar motif amino acid sequence containing compound and an amino acid residue in the CDR2 of the anti-helicar antibody, whereby the CDR2 is determined according to Kabat.

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