A dry powder inhaler with a blister folding device is provided. The inhaler comprises a housing to receive a single blister containing a dose of medicament for inhalation by a user, a mouthpiece through which a dose of medicament is inhaled by a user and a blister opening device. The blister opening device comprises a blister support element for supporting a blister containing a dose of medicament for inhalation by a user, and a blister folding element co-operable with the blister support element. The blister folding element and the blister support element are movable relative to each other between a first position, for insertion of said blister into or onto the blister support element, and a second, burst, position in which the blister folding element has co-operated with the blister support element. Movement from the first position to the second position causes two spaced apart portions of said blister to each fold relative to the remainder of the blister and against the blister support element along a respective fold line to produce two spaced apart openings such that, when a user inhales through the mouthpiece, an airflow through the blister via the two openings is generated to entrain the dose contained therein and carry it out of the blister and via the mouthpiece into the user's airway. Each opening extends along the circumference of the blister bowl, beginning and terminating at points located on the fold line. No piercing of the blister is required.La présente invention concerne un inhalateur à poudre sèche comprenant un dispositif de pliage de plaquette alvéolaire. L'inhalateur comprend un logement destiné à recevoir une plaquette alvéolaire unique contenant une dose de médicament destinée à être inhalée par un utilisateur, un embout buccal à travers lequel une dose de médicament est inhalée par un utilisateur et un dispositif d'ouverture de plaquette alvéolaire. Le dispositif d'ouverture de plaquette alvéolaire comprend un élément de support de plaquette
