The presentinvention relates generally tosystems and methods for storing,shipping and using skin equivalentsmade by organotypic culture. Inparticular, the present inventionrelates to systems and methods forproducing, transporting, storing andusing skin equivalents producedby organotypic culture at reducedtemperatures, preferably from 2-8degrees Celsius. The methodsinclude sterile packaging of the graftsso that the sterility and integrity ofthe package is maintained until thetime of use for grafting purposes.