Michael Dobosz,Christian Kein,Johannes Sam,Werner Scheuer
申请号：
US13383197
公开号：
US20120226119A1
申请日:
2010.07.09
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to non-invasive methods of and uses for in vivo imaging tumor vasculature in a subject comprising detecting a fluorescence labelled anti-CD31 antibody. In a further aspect the present invention relates to non-invasive methods of and uses for in vivo monitoring the therapeutic efficacy of an anti-angiogenic agent in a subject comprising detecting a fluorescence labelled anti-CD31 antibody. In addition, a kit for use in the methods of the present invention is provided which comprises a fluorescence labelled anti-CD31 antibody and means for near-infrared fluorescence imaging to detect the antibody in a subject.
