PROBLEM TO BE SOLVED: To provide a guide wire capable of expanding a narrowed portion without being shaped by an operator. A guide wire 100 includes a long core member 110, a lumen body 120 that covers the periphery of a tip portion of the core member, and low-density and high-density materials having different densities, and the tip of the lumen body. It has a tip fixing portion 131 that is joined to the tip portion of the portion and the core member and fixes the tip end of the lumen body to the tip end portion of the core member. The tip fixing portion, the portion joined to the tip fixing portion of the core member, and the portion joined to the tip fixing portion of the lumen body constitute the tip tip portion 180. The center of gravity M of the tip tip portion deviates from the central axis C of the lumen body. When the plane S1 including the central axis and orthogonal to the perpendicular line L from the center of gravity to the central axis is defined as a boundary, the tip tip portion includes a first region A1 in which the center of gravity is not located and a second region A2 in which the center of gravity is located. Has. The high-density material is contained more in the second region than in the first region. [Selection diagram] Fig. 2【課題】術者が形状付けしなくても狭窄部を押し広げることができるガイドワイヤを提供する。【解決手段】ガイドワイヤ100は、長尺なコア部材110と、コア部材の先端部の周囲を覆う管腔体120と、密度の異なる低密度材料および高密度材料を含み、管腔体の先端部およびコア部材の先端部に接合され、管腔体の先端をコア部材の先端に固定する先端固定部131と、を有する。先端固定部と、コア部材の先端固定部に接合された部分と、管腔体の先端固定部に接合された部分とは、先端チップ部180を構成する。先端チップ部の重心Mは、管腔体の中心軸Cからずれている。中心軸を含み、重心から中心軸への垂線Lと直交する平面S1を境界とした場合に、先端チップ部は、重心の位置しない第1領域A1と、重心の位置する第2領域A2と、を有する。高密度材料は、第1領域よりも第2領域に多く含まれている。【選択図】図2