T S SRIDHAR,PRABHU JYOTHI S,KORLIMARLA ARUNA,REMACLE JOS
申请号：
IN2515/CHE/2015
公开号：
IN2015CH02515A
申请日:
2015.05.19
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
ABSTRACT METHOD FOR IDENTIFICATION OF A DEFICIENT BRCA1 FUNCTION The present invention is related to an in vitro method for identifying deficient BRCA1 function in a test biological sample obtained from a human individual, said method comprising the steps of: - Assaying the test sample to determine an expression profile of at least BRCA1 gene and ID4 gene and - Establishing the ratio of BRCA1 to ID4 gene expression Wherein a BRCA1/ID4 ratio lower than a threshold value is used as positive criterion for identification of the deficient BRCA1 function in the tested sample. Figure 1
