Laurèn Danielle Bailey,Yingzhi Bi,Shuai Chen,Bruce D. Dorsey,Dimitar B. Gotchev,Richard James Holland,Ramesh Kakarla,Duyan Nguyen,Mark Christopher Wood
申请号:
US16834577
公开号:
US20200261432A1
申请日:
2020.03.30
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention includes substituted pyridinone-containing tricyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infection in a patient. In certain embodiments, the compounds and compositions of the invention inhibit and/or reduce HBsAg secretion.