Ekambar R. Kandimalla,Tao Lan,Yukui Li,Dong Yu,Daqing Wang,Mallikarjuna Putta,Sudhir Agrawal
申请号：
US14284938
公开号：
US09243050B2
申请日:
2014.05.22
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8.
