1-(PYRIMIDIN-2-YL)-1H-INDAZOLES HAVING BUB1 KINASE INHIBITING ACTIVITY

• 收藏
• 分享

专利权人:

BAYER PHARMA AKTIENGESELLSCHAFT

发明人:

HITCHCOCK, Marion,HILGER, Christoph-Stephan,MENGEL, Anne,BRIEM, Hans,SIEMEISTER, Gerhard,FERNANDEZ-MONTALVAN, Amaury, Ernesto,SCHRÖDER, Jens,PREUSSE, Cornelia

申请号：

EPEP2017/054733

公开号：

WO2017/148995A1

申请日:

2017.03.01

申请国别(地区):

WO

年份:

2017

代理人:

摘要：

The present invention relates to Bub1 kinase (= Budding uninhibited by benzimidazole kinase) inhibiting 1-(pyrimidin-2-yl)-1H-indazole compounds of formula (I), i.e. which therefore have potential to treat hyperprofilerative diseases such as cancer.La présente invention concerne des composés 1-(pyrimidin-2-yl)-1H-indazole de formule (I) inhibant la Bub1 kinase (= Bourgeonnement empêché par la benzimidazole kinase), ces composés ayant donc le potentiel pour traiter les maladies hyperprolifératives telles que le cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/