Use of LRIG1 as a biomarker for identifying a subject for application of anti-c-Met antibodies
- 专利权人:
- 发明人:
- Ji Min Lee,Kyung Ah Kim,Bo Gyou Kim
- 申请号:
- US13949041
- 公开号:
- US09213032B2
- 申请日:
- 2013.07.23
- 申请国别(地区):
- US
- 年份:
- 2015
- 代理人:
- 摘要:
- A method of identifying a cell sample or subject suitable for treatment with an anti-c-Met antibody or antigen-binding fragment thereof that specifically binds to an epitope within a SEMA domain of a c-Met protein by determining the presence of LRIG1 in a cell sample from the subject, as well as related methods and compositions.
- 来源网站:
- 中国工程科技知识中心
相关发明人
相关专利
- APPLICATION OF C-MET PROTEIN FOR PREDICTING THE EFFICIENCY OF ANTIBODIES TO THE HEPATOCYTES GROWTH FACTOR (FRG) IN PATIENTS WITH TREATMENT AND STOMACH
- FUSION PROTEIN COMPRISING ANTIFREEZE PROTEIN AND HUMAN EPIDERMAL GROWTH FACTOR WITH INCREASED ANTI-OXIDANT ACTIVITY AND SKIN CELL PROLIFERATION EFFECT AND COSMETIC COMPOSITION FOR ANTI-WRINKLE COMPRISING THE SAME AS EFFECTIVE COMPONENT
- נוגדן הנקשר באופן ספציפי לאפיטופ ב sema domain של c–met
- COMPUESTOS ÚTILES COMO INMUNOMODULARES
- Fusion protein comprising antifreeze protein and human epidermal growth factor with increased anti-oxidant activity and skin cell proliferation effect and cosmetic composition for anti-wrinkle comprising the same as effective component