The Johns Hopkins University;OPKO Ireland Global Holdings, Ltd.
发明人:
申请号:
EP06721850.3
公开号:
EP1883626B1
申请日:
2006.04.25
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention provides novel 16,23-diene 25-oxime ether analogs of 1,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the novel compound of the invention are useful for treating diseases which benefit from a modulation of the levels of 1,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.