DALEY Donald John,MONTANA John Gary,HYND George,TERAMOTO Mitsuru,ITO Takahiro
申请号:
EP17799327
公开号:
EP3476835A4
申请日:
2017.05.15
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Crystals of [8-chloro-3-(4-chlorobenzyl)-4-difluoromethoxy- 2-ethylquinolin-5-yloxy]acetic acid L-lysine salt, i.e., a crystal A which has peaks at diffraction angles 2¸ = 6.0°, 10.0°, 10.7°, 12.1°, 18.4°, 19.2° and 20.1° in powder X-ray diffraction spectra and a crystal B which has peaks at diffraction angles 2¸ = 6.0°, 11.7°, 12.4°, 15.2°, 16.4°, 20.3° and 22.6° in powder X-ray diffraction spectra. These crystals are chemically stable and have excellent thermal stability and physical properties, and are therefore suitable as medicinal substances.