Peritoneal dialysis fluid, including a compound (GSK) - 3, in particular activity (GSK) - 3b, which inhibits cholesterol synthetase activity, is used to prevent infectious and non infectious complications, such as peritoneum membrane inflammation, injury, damage and failure, barrier failure and detachment Intermediate cells. Claim 2: the peritoneal dialysis fluid of claim 1,The characteristic is that peritoneal dialysate is selected from carbohydrate based dialysate and amino acid based dialysate groups. 109. Claim 4: peritoneal dialysis fluid, characterized by any of the above claims, which is based on icodextrina. 11. Claim 11: peritoneal dialysis fluid or complex fluid according to any one of the above claims, which is characterized in that compounds inhibiting the activity of glycerin octyl ester (GSK) - 3 are selected from groups of lithium, tideglusib and np-103,Inhibitor I gsk-3b (tdzd-8, 4-bencil-2-met-1, 2, 4-tiadiazolidino-3, 5-diona),Inhibitor II gsk-3b (2-TiO (3-yodobencil) - 5 - (1-piridil) - [1,3,4] - oxadiazol,GSK-3 (sb-216763, 3 - (2, 4-dichlorophenyl) - 4 - (1-methyl-1h-indoli-3-il) - 1h-pirol-2, 5-dioxy,The ninth inhibitor of GSK-3 (bio, (2Z, 3e) - 6-bromodiphenyl ether-3-oxygen)；The sixth inhibitor of gsk-3b (2-chloro-1 - (4,5-dibromo-thiophene-2-il) - ethane)Gsk-3b (2,4-dibromoacetone) inhibitor VII,Gsk-3b (AR a014418, N - (4-methoxybenzene) - N - (5-nitro-1, 3-thiazol-2-il) urea；The X inhibitor of GSK-3 (bio acetoxima, (2Z, 3e) - 6-bromodiphenyl ether-3-acetoxima),inhibidor XI de GSK-3b (3- (1- (3-hidroxipropil) -1H-pirrolo 2 3-bipiridin-3-il -4-pirazin-2-il-pirrol-2 5-diona 7AIPM)The thirteenth inhibitor of gsk-3b (5-met-1h-pirazol-3-il) - (2-fenilquinazolin-4-il) amine,The 12th inhibitor of gsk-3b (tws119, 3 - [6 - (3-aminofenil) - 7h pirrolo [2, 3-d] pirimidin-4-il] oxyphenol；Methane, the 18th inhibitor of gsk-3b (2 - (chloro-4 - (4-tiofen-2-il-pirimidin-2-ilamino) - phenyl),Gsk-3b (bio acetoxime, (2Z, 3e) - 6-bromodiphenyl ether-3-acetone) i
