Lactic acid bacteria, innate immune activators derived from the lactic acid bacteria, infectious disease preventive and therapeutic agents, and food and drink
It is to provide a lactic acid bacterium having a high ability to activate innate immunity, and further to provide an innate immunity activator containing the lactic acid bacterium or one derived from the lactic acid bacterium, an infectious disease preventive / therapeutic agent, and a food or drink containing them. This is a lactic acid bacterium belonging to the genus Lactobacillus whose NITE's NPMD accession number is NITE BP-02005, the lactic acid bacterium or a lactic acid bacterium naturally or artificially mutated thereof, and having an innate immune activation ability. Effective lactic acid bacteria having the base sequence of the 16S rDNA region represented by SEQ ID NO: 1, the lactic acid bacteria, dead bacteria of the lactic acid bacteria, or a natural immunity activator comprising the processed product of the lactic acid bacteria, and the peptidoglycan of the lactic acid bacteria are effective The said subject was solved by the infectious disease prevention-treatment agent contained as a component, and the food-drinks containing them.高い自然免疫活性化能を有する乳酸菌を提供することであり、更に該乳酸菌又は該乳酸菌に由来するものを含有する自然免疫活性化剤、感染症予防治療剤、それらを含有する飲食品を提供することを課題とし、ＮＩＴＥのＮＰＭＤにおける受託番号がＮＩＴＥ ＢＰ－０２００５であるラクトバチルス（Lactobacillus）属に属する乳酸菌、該乳酸菌又はその自然的若しくは人工的に変異した乳酸菌であって自然免疫活性化能を有する乳酸菌、配列番号１で示される１６Ｓ ｒＤＮＡ領域の塩基配列を有する乳酸菌、該乳酸菌、該乳酸菌の死菌又は該乳酸菌の処理物を有効成分とする自然免疫活性化剤、該乳酸菌のペプチドグリカンを有効成分として含有する感染症予防治療剤、それらを含有する飲食品によって上記課題を解決した。
