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EXTENDED RELEASE FORMULATION
专利权人:
Shionogi & Co.; Ltd.
发明人:
MIZUTANI, Naoya,KIMURA, Go,NISHINO, Yukiko,SAKUMA, Satoshi
申请号:
EP15743275
公开号:
EP3088002A4
申请日:
2015.01.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention is a sustained release formulation which is capable of cotrolling dissolution of a drug and of enduring peristaltic movement of the gastrointestinal tract. Specifically, the present invention is: a solid dosage form comprising a drug, croscarmellose sodium, an alkali metal salt or an alkoxide, and an alkali agent, wherein the alkali metal salt is a sodium salt or a potassium salt, and the alkali agent is a magnesium oxide or a solid dosage form comprising a drug, croscarmellose sodium, an alkali metal salt or an alkoxide, and a water soluble polymer or a hydrophobic base, wherein the alkali metal salt is a sodium salt or a potassium salt. The present invention is thus capable of providing an extended release formulation that controls dissolution of a drug and endures peristaltic movement of the gastrointestinal tract.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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