The present invention relates to a hemostasis valve device which allows a wire or a catheter to be inserted into the left or right coronary artery via the femoral artery or an arm artery when a Cardiac Catheterization or Percutaneous Transluminal Coronary Angioplasty operation is performed, wherein two independent sealing members are opened and closed by press and release actions of push buttons coupled to a body and the rotation of a fastening tube, respectively, so that the leakage or blood or the inflow of outside air is simply and effectively blocked during the operation, and a drug influx tube for allowing a medicine such as a thrombolytic drug to flow into a patient during the operation pivots and is adjusted in a stepwise manner within a certain range of angles according to body conditions or movements of the patient.
