Stephen F. BELLOMO,Alex OKUN,Yaron FUERST,David SHALHEVET,Elisha AMIR,Mordechay BUKHMAN
申请号:
US13686939
公开号:
US20130090669A1
申请日:
2012.11.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Embodiments of the present invention provide Dermal Micro-organs (DMOs), methods and apparatuses for harvesting the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. Exemplary embodiments of the invention provide a genetically modified dermal micro-organ expressing at least one recombinant gene product. Some embodiments of the invention provide methods and apparatuses for implanting a genetically modified DMO.