Ellwood, Charles,Lyssikatos, Joseph P.,Gazzard, Lewis J.,Kintz, Samuel S.,Dyke, Hazel Joan,Gancia, Emanuela,Goodacre, Simon Charles,Williams, Karen,Macleod, Calum,Chen, Huifen
申请号:
AU2009258124
公开号:
AU2009258124C1
申请日:
2009.06.10
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The invention relates to 1,7-diazacarbazole compounds of Formula (I), (I-a) and (I-b) which are useful as kinase inhibitors, more specifically useful as checkpoint kinase 1 (chkl) inhibitors, thus useful as cancer therapeutics. The invention also relates to compositions, more specifically pharmaceutical compositions comprising these compounds and methods of using the same to treat various forms of cancer and hyperproliferative disorders, as well as methods of using the compounds for in