Wolfgang Walther,Peter M. Schlag,Dennis Kobelt,Manuel Schmidt
申请号:
US13820888
公开号:
US20130273084A1
申请日:
2011.09.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to the use of a DNA expression construct comprising a dumbbell-shaped circular strand of deoxyribonucleic acids and provides such a construct with a double-stranded stem and single-stranded loops located at both ends of the stem, wherein the stem comprises complementary deoxyribonucleic acids of the circular strand with a promotor sequence, a coding sequence and a termination signal to be administered by jet injection for the treatment of cancer.