Amide containing carbonyl bearing adamantyl substituents as selective inhibitors of the 11-beta-hydroxysteroid dehydrogenase type i enzyme

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专利权人:

ABBVIE INC.

发明人:

申请号：

IL21342511

公开号：

IL213425A

申请日:

2011.06.06

申请国别(地区):

IL

年份:

2015

代理人:

摘要：

The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.

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