TOMITA NAOKI,KAJII SHIGEO,CARY DOUGLAS ROBERT,TOMITA DAISUKE,IMAMURA SHINICHI,TSUCHIDA KEN,MATSUDA SATORU,HARA RYUJIRO
申请号:
TN2014000042
公开号:
TN2014000042A1
申请日:
2014.01.29
申请国别(地区):
TN
年份:
2015
代理人:
摘要:
The present invention provides a compound which has an inhibitory activity on lysine-specific demethylase 1 and is useful as a medicinal agent such as a prophylactic or therapeutic agent for cancer and central nervous system diseases. The present invention relates to a compound represented by formula (I) [wherein A represents a hydrocarbon or heterocyclic ring group which may have a substituent; R represents H or a hydrocarbon or heterocyclic ring group which may have a substituent; A and R may be bound together to form a ring which may have a substituent; Q1, Q2, Q3 and Q4 independently represent a hydrogen atom or a substituent; Q1 and Q2 or Q3 and Q4 may be bound together to form a ring which may have a substituent; X represents H or a linear hydrocarbon or saturated cyclic group which may have a substituent; Y1, Y2 and Y3 independently represent H or a hydrocarbon or heterocyclic ring group which may have a substituent; X and Y1 or Y1 and Y2 may be bound together to form a ring which may have a substituent; and Z1, Z2 and Z3 independently represent H or a substituent] or a salt thereof.