A method of predicting a healthcare event includes: receiving via an input device, classifying personal information for each of a plurality of persons; collecting measurements of at least one health indicator during a predefined learning period; creating a personal physiological pattern profile, based on the collected data; associating each of the plurality of persons to a physiological cluster based on each person's personal physiological pattern profile and based on the classifying personal information of each of the plurality of persons; creating, for each physiological cluster, a health indicator deviation pattern for the healthcare event; continuously monitoring values of the health indicator of the person; and determining an occurrence probability of the healthcare event when the monitored indicators deviate from the personal physiological pattern profile. A system for predicting a healthcare event is also disclosed.